
The Boeing 777-200 aircraft had 227 passengers, including two infants, and 12 crew members on board, the airline said in a statement. The passengers were of 13 different nationalities.
"Our team is currently calling the next-of-kin of passengers and crew," the airlines' group chief executive officer, Ahmad Jauhari Yahya, said in a statement. "Focus of the airline is to work with the emergency responders and authorities and mobilize its full support."
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Flight MH370 departed from Kuala Lumpur at 12:41 a.m. Saturday local time, according to a statement from the airline. Air traffic control in Subang lost contact with it two hours later.
It was scheduled to land in Beijing at 6:30 a.m. the same day.
Malaysia Airlines said search and rescue teams had been activated.

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